BDBM243189 (R)-N-(1-(3,4-dihydro-2,7-naphthyridin- 2(1H)-yl)propan-2-yl)-4-(5- (trifluoromethyl)-1,2,4-oxadiazol-3- yl)benzamide::US10053434, 18

SMILES: C[C@H](CN1CCc2ccncc2C1)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F

InChI Key: InChIKey=ZHVSKKPOSCSUPK-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HDAC4 (Homo sapiens (Human))	BDBM243189 ((R)-N-(1-(3,4-dihydro-2,7-naphthyridin- 2(1H)-yl)p...) Show SMILES C[C@H](CN1CCc2ccncc2C1)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F |r| Show InChI InChI=1S/C21H20F3N5O2/c1-13(11-29-9-7-14-6-8-25-10-17(14)12-29)26-19(30)16-4-2-15(3-5-16)18-27-20(31-28-18)21(22,23)24/h2-6,8,10,13H,7,9,11-12H2,1H3,(H,26,30)/t13-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
CHDI FOUNDATION, INC. US Patent					Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...				US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ
					More data for this Ligand-Target Pair