BindingDB logo
myBDB logout

null

SMILES: O=C1NCCN(c2ncc(o2)-c2cccc(Nc3nccc(n3)[N+]#[C-])c2)C11CC1

InChI Key: InChIKey=STGNCRRWAKHSID-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243346   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM243346
PNG
(2-{3-[2-(8-Oxo-4,7- diaza-spiro[2.5]oct-4-yl)- oxa...)
Show SMILES O=C1NCCN(c2ncc(o2)-c2cccc(Nc3nccc(n3)[N+]#[C-])c2)C11CC1
Show InChI InChI=1S/C20H17N7O2/c1-21-16-5-8-23-18(26-16)25-14-4-2-3-13(11-14)15-12-24-19(29-15)27-10-9-22-17(28)20(27)6-7-20/h2-5,8,11-12H,6-7,9-10H2,(H,22,28)(H,23,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/a7.825



AB SCIENCE

US Patent


Assay Description
SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...

US Patent US10053455 (2018)


BindingDB Entry DOI: 10.7270/Q27946PV
More data for this
Ligand-Target Pair