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SMILES: Cc1ccnc(Nc2cccc(c2)-c2cnc(o2)N2CCNC(=O)C22CC2)c1

InChI Key: InChIKey=PRLBXSIKVFRDNO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243365   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM243365
PNG
(4-{5-[3-(4-Methyl- pyridin-2-ylamino)- phenyl]oxaz...)
Show SMILES Cc1ccnc(Nc2cccc(c2)-c2cnc(o2)N2CCNC(=O)C22CC2)c1
Show InChI InChI=1S/C21H21N5O2/c1-14-5-8-22-18(11-14)25-16-4-2-3-15(12-16)17-13-24-20(28-17)26-10-9-23-19(27)21(26)6-7-21/h2-5,8,11-13H,6-7,9-10H2,1H3,(H,22,25)(H,23,27)
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 1.25E+3n/an/an/an/a7.825



AB SCIENCE

US Patent


Assay Description
SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...

US Patent US10053455 (2018)


BindingDB Entry DOI: 10.7270/Q27946PV
More data for this
Ligand-Target Pair