null

SMILES: ONC(=O)CCCCCCC(=O)Nc1cccc(c1)-c1cn(Cc2ccccc2)nn1

InChI Key: InChIKey=QWAGLXWBHCFGBD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 24349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM24349 (N-[3-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]-N'-hy...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1cccc(c1)-c1cn(Cc2ccccc2)nn1 Show InChI InChI=1S/C23H27N5O3/c29-22(13-6-1-2-7-14-23(30)26-31)24-20-12-8-11-19(15-20)21-17-28(27-25-21)16-18-9-4-3-5-10-18/h3-5,8-12,15,17,31H,1-2,6-7,13-14,16H2,(H,24,29)(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14.5	n/a	n/a	n/a	n/a	7.5	25
University of Illinois at Chicago					Assay Description The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...				J Med Chem 51: 3437-48 (2008) Article DOI: 10.1021/jm701606b BindingDB Entry DOI: 10.7270/Q2ZC815S
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM24349 (N-[3-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]-N'-hy...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1cccc(c1)-c1cn(Cc2ccccc2)nn1 Show InChI InChI=1S/C23H27N5O3/c29-22(13-6-1-2-7-14-23(30)26-31)24-20-12-8-11-19(15-20)21-17-28(27-25-21)16-18-9-4-3-5-10-18/h3-5,8-12,15,17,31H,1-2,6-7,13-14,16H2,(H,24,29)(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	7.5	25
University of Illinois at Chicago					Assay Description The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...				J Med Chem 51: 3437-48 (2008) Article DOI: 10.1021/jm701606b BindingDB Entry DOI: 10.7270/Q2ZC815S
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM24349 (N-[3-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]-N'-hy...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1cccc(c1)-c1cn(Cc2ccccc2)nn1 Show InChI InChI=1S/C23H27N5O3/c29-22(13-6-1-2-7-14-23(30)26-31)24-20-12-8-11-19(15-20)21-17-28(27-25-21)16-18-9-4-3-5-10-18/h3-5,8-12,15,17,31H,1-2,6-7,13-14,16H2,(H,24,29)(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago					Assay Description The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...				J Med Chem 51: 3437-48 (2008) Article DOI: 10.1021/jm701606b BindingDB Entry DOI: 10.7270/Q2ZC815S
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM24349 (N-[3-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]-N'-hy...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1cccc(c1)-c1cn(Cc2ccccc2)nn1 Show InChI InChI=1S/C23H27N5O3/c29-22(13-6-1-2-7-14-23(30)26-31)24-20-12-8-11-19(15-20)21-17-28(27-25-21)16-18-9-4-3-5-10-18/h3-5,8-12,15,17,31H,1-2,6-7,13-14,16H2,(H,24,29)(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago					Assay Description The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...				J Med Chem 51: 3437-48 (2008) Article DOI: 10.1021/jm701606b BindingDB Entry DOI: 10.7270/Q2ZC815S
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM24349 (N-[3-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]-N'-hy...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1cccc(c1)-c1cn(Cc2ccccc2)nn1 Show InChI InChI=1S/C23H27N5O3/c29-22(13-6-1-2-7-14-23(30)26-31)24-20-12-8-11-19(15-20)21-17-28(27-25-21)16-18-9-4-3-5-10-18/h3-5,8-12,15,17,31H,1-2,6-7,13-14,16H2,(H,24,29)(H,26,30)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago					Assay Description The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...				J Med Chem 51: 3437-48 (2008) Article DOI: 10.1021/jm701606b BindingDB Entry DOI: 10.7270/Q2ZC815S
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM24349 (N-[3-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]-N'-hy...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1cccc(c1)-c1cn(Cc2ccccc2)nn1 Show InChI InChI=1S/C23H27N5O3/c29-22(13-6-1-2-7-14-23(30)26-31)24-20-12-8-11-19(15-20)21-17-28(27-25-21)16-18-9-4-3-5-10-18/h3-5,8-12,15,17,31H,1-2,6-7,13-14,16H2,(H,24,29)(H,26,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago					Assay Description The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...				J Med Chem 51: 3437-48 (2008) Article DOI: 10.1021/jm701606b BindingDB Entry DOI: 10.7270/Q2ZC815S
					More data for this Ligand-Target Pair