BDBM243607 US9428456, 1.338

SMILES: CCC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(Cl)cn3)c2)CC1

InChI Key: InChIKey=WHJDUGBBTKHXRG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 7 (CXCR7) (Homo sapiens (Human))	BDBM243607 (US9428456, 1.338) Show SMILES CCC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(Cl)cn3)c2)CC1 Show InChI InChI=1S/C24H31ClN4O2/c1-4-24(2,3)28-22(30)18-10-12-29(13-11-18)16-17-6-5-7-20(14-17)27-23(31)21-9-8-19(25)15-26-21/h5-9,14-15,18H,4,10-13,16H2,1-3H3,(H,27,31)(H,28,30)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.800	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD US Patent					Assay Description CHO-K1 CXCR7 b-arrestin cells are detached from culture dishes with a cell dissociation buffer (Invitrogen, #13151-014) and collected in growing medi...				US Patent US9428456 (2016) BindingDB Entry DOI: 10.7270/Q29022PZ
					More data for this Ligand-Target Pair