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SMILES: Brc1cccnc1C(=O)Nc1cccc(CN2CCC(CC2)C(=O)NC2CCCCC2)c1

InChI Key: InChIKey=VHLCOQBTWAJPDI-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243754   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Atypical chemokine receptor 3


(Homo sapiens (Human))		BDBM243754
PNG
(US9428456, 1.085)
Show SMILES Brc1cccnc1C(=O)Nc1cccc(CN2CCC(CC2)C(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C25H31BrN4O2/c26-22-10-5-13-27-23(22)25(32)29-21-9-4-6-18(16-21)17-30-14-11-19(12-15-30)24(31)28-20-7-2-1-3-8-20/h4-6,9-10,13,16,19-20H,1-3,7-8,11-12,14-15,17H2,(H,28,31)(H,29,32)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/a37



ACTELION PHARMACEUTICALS LTD

US Patent


Assay Description
CHO-K1 CXCR7 b-arrestin cells are detached from culture dishes with a cell dissociation buffer (Invitrogen, #13151-014) and collected in growing medi...

US Patent US9428456 (2016)


BindingDB Entry DOI: 10.7270/Q29022PZ
More data for this
Ligand-Target Pair