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SMILES: FC(F)(F)c1ccc(nc1)C(=O)Nc1ccc(Cl)c(CN2CCC(CC2)C(=O)NC2CCCC2)c1

InChI Key: InChIKey=WWBNUPXWSXZUEL-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243791   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Atypical chemokine receptor 3


(Homo sapiens (Human))		BDBM243791
PNG
(US9428456, 1.220)
Show SMILES FC(F)(F)c1ccc(nc1)C(=O)Nc1ccc(Cl)c(CN2CCC(CC2)C(=O)NC2CCCC2)c1
Show InChI InChI=1S/C25H28ClF3N4O2/c26-21-7-6-20(32-24(35)22-8-5-18(14-30-22)25(27,28)29)13-17(21)15-33-11-9-16(10-12-33)23(34)31-19-3-1-2-4-19/h5-8,13-14,16,19H,1-4,9-12,15H2,(H,31,34)(H,32,35)
UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/a37



ACTELION PHARMACEUTICALS LTD

US Patent


Assay Description
CHO-K1 CXCR7 b-arrestin cells are detached from culture dishes with a cell dissociation buffer (Invitrogen, #13151-014) and collected in growing medi...

US Patent US9428456 (2016)


BindingDB Entry DOI: 10.7270/Q29022PZ
More data for this
Ligand-Target Pair