BindingDB logo
myBDB logout

null

SMILES: CC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(F)cc3)c2)CC1

InChI Key: InChIKey=IRRVONVFZZUAGM-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243794   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Atypical chemokine receptor 3


(Homo sapiens (Human))		BDBM243794
PNG
(US9428456, 1.223)
Show SMILES CC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(F)cc3)c2)CC1
Show InChI InChI=1S/C24H30FN3O2/c1-24(2,3)27-23(30)19-11-13-28(14-12-19)16-17-5-4-6-21(15-17)26-22(29)18-7-9-20(25)10-8-18/h4-10,15,19H,11-14,16H2,1-3H3,(H,26,29)(H,27,30)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.5n/an/an/a37



ACTELION PHARMACEUTICALS LTD

US Patent


Assay Description
CHO-K1 CXCR7 b-arrestin cells are detached from culture dishes with a cell dissociation buffer (Invitrogen, #13151-014) and collected in growing medi...

US Patent US9428456 (2016)


BindingDB Entry DOI: 10.7270/Q29022PZ
More data for this
Ligand-Target Pair