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SMILES: [O-][n+]1cc(F)ccc1C(=O)Nc1cccc(CN2CCC(CC2)C(=O)NC2CCCC2)c1

InChI Key: InChIKey=JHTPLNCKOHHXSQ-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243846   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Atypical chemokine receptor 3


(Homo sapiens (Human))		BDBM243846
PNG
(US9428456, 4.006)
Show SMILES [O-][n+]1cc(F)ccc1C(=O)Nc1cccc(CN2CCC(CC2)C(=O)NC2CCCC2)c1
Show InChI InChI=1S/C24H29FN4O3/c25-19-8-9-22(29(32)16-19)24(31)27-21-7-3-4-17(14-21)15-28-12-10-18(11-13-28)23(30)26-20-5-1-2-6-20/h3-4,7-9,14,16,18,20H,1-2,5-6,10-13,15H2,(H,26,30)(H,27,31)
UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/a37



ACTELION PHARMACEUTICALS LTD

US Patent


Assay Description
CHO-K1 CXCR7 b-arrestin cells are detached from culture dishes with a cell dissociation buffer (Invitrogen, #13151-014) and collected in growing medi...

US Patent US9428456 (2016)


BindingDB Entry DOI: 10.7270/Q29022PZ
More data for this
Ligand-Target Pair