BDBM24393 2,3-dichloro-N-{1-[(2R)-2,3-dihydroxypropyl]-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl}-4H-thieno[3,2-b]pyrrole-5-carboxamide::3,4-dihydro-2-quinolone (DHQ) derivative, 32
SMILES: OC[C@H](O)CN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1
InChI Key: InChIKey=OZBWIUILLXYRCQ-RWANSRKNSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Glycogen phosphorylase, liver form (Homo sapiens (Human)) | BDBM24393 (2,3-dichloro-N-{1-[(2R)-2,3-dihydroxypropyl]-2-oxo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format.... | Bioorg Med Chem Lett 17: 394-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.037 BindingDB Entry DOI: 10.7270/Q2TM78DM | |||||||||||
More data for this Ligand-Target Pair |