BDBM243974 US9428456, 4.020

SMILES: CC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(F)cn3)c2)CC1

InChI Key: InChIKey=BQVINWDFLPALKA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 7 (CXCR7) (Homo sapiens (Human))	BDBM243974 (US9428456, 4.020) Show SMILES CC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(F)cn3)c2)CC1 Show InChI InChI=1S/C23H29FN4O2/c1-23(2,3)27-21(29)17-9-11-28(12-10-17)15-16-5-4-6-19(13-16)26-22(30)20-8-7-18(24)14-25-20/h4-8,13-14,17H,9-12,15H2,1-3H3,(H,26,30)(H,27,29)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD US Patent					Assay Description CHO-K1 CXCR7 b-arrestin cells are detached from culture dishes with a cell dissociation buffer (Invitrogen, #13151-014) and collected in growing medi...				US Patent US9428456 (2016) BindingDB Entry DOI: 10.7270/Q29022PZ
					More data for this Ligand-Target Pair