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SMILES: Cc1cc(N(Cc2ccccc2)c2ccc3ccccc3c2)n2ncnc2n1

InChI Key: InChIKey=GORJITBKOQHVAT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24405   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Plasmodium falciparum (isolate 3D7))		BDBM24405
PNG
(N-benzyl-5-methyl-N-(naphthalen-2-yl)-[1,2,4]triaz...)
Show SMILES Cc1cc(N(Cc2ccccc2)c2ccc3ccccc3c2)n2ncnc2n1
Show InChI InChI=1S/C23H19N5/c1-17-13-22(28-23(26-17)24-16-25-28)27(15-18-7-3-2-4-8-18)21-12-11-19-9-5-6-10-20(19)14-21/h2-14,16H,15H2,1H3
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.30E+4n/an/an/an/a8.020



University of Texas Southwestern Medical Center at Dallas



Assay Description
The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...

J Med Chem 51: 3649-53 (2008)


Article DOI: 10.1021/jm8001026
BindingDB Entry DOI: 10.7270/Q2PV6HNF
More data for this
Ligand-Target Pair