BDBM244066 US9428478, TG2-181-1
SMILES: CC(=O)c1ccc(NCC(=O)N2CCN(CC2)c2ccccc2N)cc1
InChI Key: InChIKey=XBLCBNURXYAPJG-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Xanthine dehydrogenase/oxidase (Homo sapiens (Human)) | BDBM244066 (US9428478, TG2-181-1) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.00E+10 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University US Patent | Assay Description Assay controls. To rule out interference with either Nox2 or Nox4 luminescence assays, two approaches are used. In one, xanthine oxidase replaces the... | US Patent US9428478 (2016) BindingDB Entry DOI: 10.7270/Q2RX9B09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM244066 (US9428478, TG2-181-1) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.00E+9 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University US Patent | Assay Description Nox2 activity assay for primary screening: Plasma membranes were prepared from human neutrophils, which express large amounts of Nox2, stored at W... | US Patent US9428478 (2016) BindingDB Entry DOI: 10.7270/Q2RX9B09 | |||||||||||
More data for this Ligand-Target Pair |