null
SMILES: COC(=O)c1ccc2[nH]c(cc2c1)C(=O)N1CCN(CC1)c1ccc(OC)cc1
InChI Key: InChIKey=CRLFRTQFPTXFFZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Xanthine dehydrogenase/oxidase (Homo sapiens (Human)) | BDBM244081 (US9428478, TG6-222) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >2.00E+10 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University US Patent | Assay Description Assay controls. To rule out interference with either Nox2 or Nox4 luminescence assays, two approaches are used. In one, xanthine oxidase replaces the... | US Patent US9428478 (2016) BindingDB Entry DOI: 10.7270/Q2RX9B09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM244081 (US9428478, TG6-222) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University US Patent | Assay Description Nox2 activity assay for primary screening: Plasma membranes were prepared from human neutrophils, which express large amounts of Nox2, stored at W... | US Patent US9428478 (2016) BindingDB Entry DOI: 10.7270/Q2RX9B09 | |||||||||||
More data for this Ligand-Target Pair |