BDBM244087 US9428478, TG6-238
SMILES: CCOc1ccc(cc1)N1CCN(CC1)C(=O)c1cc2cc(ccc2[nH]1)C(C)=O
InChI Key: InChIKey=QCBHXRQPTVTAQI-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Xanthine dehydrogenase/oxidase (Homo sapiens (Human)) | BDBM244087 (US9428478, TG6-238) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.00E+10 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University US Patent | Assay Description Assay controls. To rule out interference with either Nox2 or Nox4 luminescence assays, two approaches are used. In one, xanthine oxidase replaces the... | US Patent US9428478 (2016) BindingDB Entry DOI: 10.7270/Q2RX9B09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM244087 (US9428478, TG6-238) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University US Patent | Assay Description Nox2 activity assay for primary screening: Plasma membranes were prepared from human neutrophils, which express large amounts of Nox2, stored at W... | US Patent US9428478 (2016) BindingDB Entry DOI: 10.7270/Q2RX9B09 | |||||||||||
More data for this Ligand-Target Pair |