BDBM244290 US9550763, Compound I-038
SMILES: NC(=O)c1cccc(Oc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3ccc(Cl)cc3)cc2)n1
InChI Key: InChIKey=XJQQDUVNNYSCLN-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P2X purinoceptor 3 (Homo sapiens (Human)) | BDBM244290 (US9550763, Compound I-038) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.5 | n/a |
SHIONOGI & CO., LTD. US Patent | Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ... | US Patent US9550763 (2017) BindingDB Entry DOI: 10.7270/Q2V126TQ | |||||||||||
More data for this Ligand-Target Pair |