BDBM245364 US9428504, 113

SMILES: CC(C)(C)CN1CCC2(CN(c3c2c(ccc3O)-c2nc3ccc(Cl)cc3s2)c2ccccc2NC(=O)Nc2csc(Cl)n2)CC1

InChI Key: InChIKey=SVEZEMIBSMJJDU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 245364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purinergic receptor P2Y1 (Homo sapiens (Human))	BDBM245364 (US9428504, 113) Show SMILES CC(C)(C)CN1CCC2(CN(c3c2c(ccc3O)-c2nc3ccc(Cl)cc3s2)c2ccccc2NC(=O)Nc2csc(Cl)n2)CC1 Show InChI InChI=1S/C34H34Cl2N6O2S2/c1-33(2,3)18-41-14-12-34(13-15-41)19-42(24-7-5-4-6-22(24)38-32(44)40-27-17-45-31(36)39-27)29-25(43)11-9-21(28(29)34)30-37-23-10-8-20(35)16-26(23)46-30/h4-11,16-17,43H,12-15,18-19H2,1-3H3,(H2,38,40,44)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.10	-11.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...				US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD
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