BDBM24618 CG-001::N-hydroxy-4-[2-(phenylformamido)ethoxy]benzamide
SMILES: ONC(=O)c1ccc(OCCNC(=O)c2ccccc2)cc1
InChI Key: InChIKey=GXOFMHYSDHBUFQ-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM24618 (CG-001 | N-hydroxy-4-[2-(phenylformamido)ethoxy]be...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 43 | -9.94 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Celera Genomics | Assay Description HDAC activity was measured using a continuous trypsin-coupled assay. For inhibitor characterization, measurements were done using 96-well assay plat... | Mol Cancer Ther 5: 1309-17 (2006) Article DOI: 10.1158/1535-7163.MCT-05-0442 BindingDB Entry DOI: 10.7270/Q2DF6PJJ | |||||||||||
More data for this Ligand-Target Pair |