BDBM246500 (4E,6E)-1,7-bis(4-hydroxyphenyl)-4,6-heptadien-3-one (20)
SMILES: Oc1ccc(CCC(=O)\C=C\C=C\c2ccc(O)cc2)cc1
InChI Key: InChIKey=QIROPQQWKBMABC-ZPUQHVIOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pancreatic triacylglycerol lipase (Sus scrofa (Pig)) | BDBM246500 ((4E,6E)-1,7-bis(4-hydroxyphenyl)-4,6-heptadien-3-o...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 1.92E+3 | -8.11 | 9.12E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Seoul National University | Assay Description Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa... | J Enzyme Inhib Med Chem 29: 1-6 (2014) Article DOI: 10.3109/14756366.2012.742517 BindingDB Entry DOI: 10.7270/Q2DJ5DKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM246500 ((4E,6E)-1,7-bis(4-hydroxyphenyl)-4,6-heptadien-3-o...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.39E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Inhibition of ovine COX1 by colorimetric assay | Bioorg Med Chem 17: 2689-94 (2009) Article DOI: 10.1016/j.bmc.2009.02.057 BindingDB Entry DOI: 10.7270/Q2RF5XTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Ovis aries (Sheep)) | BDBM246500 ((4E,6E)-1,7-bis(4-hydroxyphenyl)-4,6-heptadien-3-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Inhibition of ovine COX2 by colorimetric assay | Bioorg Med Chem 17: 2689-94 (2009) Article DOI: 10.1016/j.bmc.2009.02.057 BindingDB Entry DOI: 10.7270/Q2RF5XTR | |||||||||||
More data for this Ligand-Target Pair |