BDBM246514 N-(5,6-dimethoxyindane-1-yl)methanesulfonamide (28)

SMILES: COc1cc2CCC(NS(C)(=O)=O)c2cc1OC

InChI Key: InChIKey=FZDYXWDIEVDTGU-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM246514 (N-(5,6-dimethoxyindane-1-yl)methanesulfonamide (28...) Show SMILES COc1cc2CCC(NS(C)(=O)=O)c2cc1OC Show InChI InChI=1S/C12H17NO4S/c1-16-11-6-8-4-5-10(13-18(3,14)15)9(8)7-12(11)17-2/h6-7,10,13H,4-5H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.20E+4	n/a	4.87E+5	n/a	n/a	n/a	n/a	n/a	n/a
Atatürk University					Assay Description The effect of novel sulfonamides 28-33 on HCA isozyme activity was determined colorimetrically using CO2-hydration method of Wilbur and Anderson29 de...				J Enzyme Inhib Med Chem 29: 35-42 (2014) Article DOI: 10.3109/14756366.2012.750311 BindingDB Entry DOI: 10.7270/Q2513X4M
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM246514 (N-(5,6-dimethoxyindane-1-yl)methanesulfonamide (28...) Show SMILES COc1cc2CCC(NS(C)(=O)=O)c2cc1OC Show InChI InChI=1S/C12H17NO4S/c1-16-11-6-8-4-5-10(13-18(3,14)15)9(8)7-12(11)17-2/h6-7,10,13H,4-5H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.15E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atatürk University					Assay Description The effect of novel sulfonamides 28-33 on HCA isozyme activity was determined colorimetrically using CO2-hydration method of Wilbur and Anderson29 de...				J Enzyme Inhib Med Chem 29: 35-42 (2014) Article DOI: 10.3109/14756366.2012.750311 BindingDB Entry DOI: 10.7270/Q2513X4M
					More data for this Ligand-Target Pair