BDBM246566 4-[(2-Isopropyl-1H-benzimidazol-1-yl)acetyl]benzenesulfonamide (1h)

SMILES: CC(C)c1nc2ccccc2n1CC(=O)c1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=YCQCKMMSYCKYMN-UHFFFAOYSA-N

Data: 5 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 246566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM246566 (4-[(2-Isopropyl-1H-benzimidazol-1-yl)acetyl]benzen...) Show SMILES CC(C)c1nc2ccccc2n1CC(=O)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H19N3O3S/c1-12(2)18-20-15-5-3-4-6-16(15)21(18)11-17(22)13-7-9-14(10-8-13)25(19,23)24/h3-10,12H,11H2,1-2H3,(H2,19,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4	n/a	n/a	n/a	7.0	n/a
Vilnius University					Assay Description The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...				J Enzyme Inhib Med Chem 29: 124-31 (2014) Article DOI: 10.3109/14756366.2012.757223 BindingDB Entry DOI: 10.7270/Q2RV0MMK
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM246566 (4-[(2-Isopropyl-1H-benzimidazol-1-yl)acetyl]benzen...) Show SMILES CC(C)c1nc2ccccc2n1CC(=O)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H19N3O3S/c1-12(2)18-20-15-5-3-4-6-16(15)21(18)11-17(22)13-7-9-14(10-8-13)25(19,23)24/h3-10,12H,11H2,1-2H3,(H2,19,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.56	n/a	n/a	n/a	7.0	n/a
Vilnius University					Assay Description The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...				J Enzyme Inhib Med Chem 29: 124-31 (2014) Article DOI: 10.3109/14756366.2012.757223 BindingDB Entry DOI: 10.7270/Q2RV0MMK
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Homo sapiens (Human))	BDBM246566 (4-[(2-Isopropyl-1H-benzimidazol-1-yl)acetyl]benzen...) Show SMILES CC(C)c1nc2ccccc2n1CC(=O)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H19N3O3S/c1-12(2)18-20-15-5-3-4-6-16(15)21(18)11-17(22)13-7-9-14(10-8-13)25(19,23)24/h3-10,12H,11H2,1-2H3,(H2,19,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	33.3	n/a	n/a	n/a	7.0	n/a
Vilnius University					Assay Description The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...				J Enzyme Inhib Med Chem 29: 124-31 (2014) Article DOI: 10.3109/14756366.2012.757223 BindingDB Entry DOI: 10.7270/Q2RV0MMK
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM246566 (4-[(2-Isopropyl-1H-benzimidazol-1-yl)acetyl]benzen...) Show SMILES CC(C)c1nc2ccccc2n1CC(=O)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H19N3O3S/c1-12(2)18-20-15-5-3-4-6-16(15)21(18)11-17(22)13-7-9-14(10-8-13)25(19,23)24/h3-10,12H,11H2,1-2H3,(H2,19,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	476	n/a	n/a	n/a	7.0	n/a
Vilnius University					Assay Description The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...				J Enzyme Inhib Med Chem 29: 124-31 (2014) Article DOI: 10.3109/14756366.2012.757223 BindingDB Entry DOI: 10.7270/Q2RV0MMK
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM246566 (4-[(2-Isopropyl-1H-benzimidazol-1-yl)acetyl]benzen...) Show SMILES CC(C)c1nc2ccccc2n1CC(=O)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H19N3O3S/c1-12(2)18-20-15-5-3-4-6-16(15)21(18)11-17(22)13-7-9-14(10-8-13)25(19,23)24/h3-10,12H,11H2,1-2H3,(H2,19,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	20	n/a	n/a	n/a	7.0	n/a
Vilnius University					Assay Description The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...				J Enzyme Inhib Med Chem 29: 124-31 (2014) Article DOI: 10.3109/14756366.2012.757223 BindingDB Entry DOI: 10.7270/Q2RV0MMK
					More data for this Ligand-Target Pair