null

SMILES: COc1ccc(cc1OC)C(N)c1cc(OC)c(OC)cc1C

InChI Key: InChIKey=HPMJGLAAZZMLCQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM246586 ((4,5-Dimethoxy-2-methylphenyl)(3,4-dimethoxyphenyl...) Show SMILES COc1ccc(cc1OC)C(N)c1cc(OC)c(OC)cc1C Show InChI InChI=1S/C18H23NO4/c1-11-8-15(21-3)17(23-5)10-13(11)18(19)12-6-7-14(20-2)16(9-12)22-4/h6-10,18H,19H2,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.95E+4	-6.00	n/a	n/a	n/a	n/a	n/a	7.4	25
Atatürk University					Assay Description CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...				J Enzyme Inhib Med Chem 29: 168-74 (2014) Article DOI: 10.3109/14756366.2012.763163 BindingDB Entry DOI: 10.7270/Q2H99447
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM246586 ((4,5-Dimethoxy-2-methylphenyl)(3,4-dimethoxyphenyl...) Show SMILES COc1ccc(cc1OC)C(N)c1cc(OC)c(OC)cc1C Show InChI InChI=1S/C18H23NO4/c1-11-8-15(21-3)17(23-5)10-13(11)18(19)12-6-7-14(20-2)16(9-12)22-4/h6-10,18H,19H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.76E+4	-5.89	n/a	n/a	n/a	n/a	n/a	7.4	25
Atatürk University					Assay Description CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...				J Enzyme Inhib Med Chem 29: 168-74 (2014) Article DOI: 10.3109/14756366.2012.763163 BindingDB Entry DOI: 10.7270/Q2H99447
					More data for this Ligand-Target Pair