null
SMILES: CCCCOc1cccc(c1)C(F)(F)CNCC(=O)N(CC)CC
InChI Key: InChIKey=MLCYIAIOTNYMPQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM247260 (US9447029, 1-32) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEWRON PHARMACEUTICALS S.P.A. US Patent | Assay Description Cells and methods: Functional inhibition of the sodium currents is studied using whole cell patch clamp methods (Hamill O. P., Marty A., Neher E., Sa... | US Patent US9447029 (2016) BindingDB Entry DOI: 10.7270/Q26T0KJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM247260 (US9447029, 1-32) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | 37 |
NEWRON PHARMACEUTICALS S.P.A. US Patent | Assay Description Test compound is dissolved in DMSO 500× the highest final concentration desired in the IC50 assay. 30 ml of deionized water is pre-warmed to 37... | US Patent US9447029 (2016) BindingDB Entry DOI: 10.7270/Q26T0KJZ | |||||||||||
More data for this Ligand-Target Pair |