BDBM247462 US9453023, 21

SMILES: C[C@H]1CCCN1C1CCC(=CC1)c1ccc(NC(=O)OCc2ccccc2)c(F)c1

InChI Key: InChIKey=PGEBLGFMKXZZNY-HXBUSHRASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 247462   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247462 (US9453023, 21) Show SMILES C[C@H]1CCCN1C1CCC(=CC1)c1ccc(NC(=O)OCc2ccccc2)c(F)c1 |r,c:10| Show InChI InChI=1S/C25H29FN2O2/c1-18-6-5-15-28(18)22-12-9-20(10-13-22)21-11-14-24(23(26)16-21)27-25(29)30-17-19-7-3-2-4-8-19/h2-4,7-9,11,14,16,18,22H,5-6,10,12-13,15,17H2,1H3,(H,27,29)/t18-,22?/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair