BDBM24781 2-phenyl-1,4-benzoquinone, 10::2-phenylcyclohexa-2,5-diene-1,4-dione::Phenyl-p-benzoquinone, 5

SMILES: O=C1C=CC(=O)C(=C1)c1ccccc1

InChI Key: InChIKey=RLQZIECDMISZHS-UHFFFAOYSA-N

Data: 3 IC50  1 Other

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 24781   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM24781 (2-phenyl-1,4-benzoquinone, 10 | 2-phenylcyclohexa-...) Show SMILES O=C1C=CC(=O)C(=C1)c1ccccc1 |c:2,6| Show InChI InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	6.5	37
Bryn Mawr College					Assay Description The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...				J Med Chem 51: 1706-18 (2008) Article DOI: 10.1021/jm7014155 BindingDB Entry DOI: 10.7270/Q2VD6WSV
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM24781 (2-phenyl-1,4-benzoquinone, 10 | 2-phenylcyclohexa-...) Show SMILES O=C1C=CC(=O)C(=C1)c1ccccc1 |c:2,6| Show InChI InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Chemistry, School of Pharmacy, Centre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa. Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...				Eur J Med Chem 135: 196-203 (2017) Article DOI: 10.1016/j.ejmech.2017.04.055 BindingDB Entry DOI: 10.7270/Q2MW2KM1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM24781 (2-phenyl-1,4-benzoquinone, 10 | 2-phenylcyclohexa-...) Show SMILES O=C1C=CC(=O)C(=C1)c1ccccc1 |c:2,6| Show InChI InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Chemistry, School of Pharmacy, Centre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa. Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...				Eur J Med Chem 135: 196-203 (2017) Article DOI: 10.1016/j.ejmech.2017.04.055 BindingDB Entry DOI: 10.7270/Q2MW2KM1
					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3 (Homo sapiens (Human))	BDBM24781 (2-phenyl-1,4-benzoquinone, 10 | 2-phenylcyclohexa-...) Show SMILES O=C1C=CC(=O)C(=C1)c1ccccc1 |c:2,6| Show InChI InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	7.45	37
Cardiff University					Assay Description Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.				J Enzym Inhib 16: 35-45 (2001) Article DOI: 10.1080/14756360109162353 BindingDB Entry DOI: 10.7270/Q2SX6BRB
					More data for this Ligand-Target Pair