BDBM24789 6-methoxy-2,2-dimethyl-2H,5H,10H-benzo[g]chromene-5,10-dione::Pyranonaphthoquinone derivative, 26

SMILES: COc1cccc2C(=O)C3=C(C=CC(C)(C)O3)C(=O)c12

InChI Key: InChIKey=QMGSLQUQZVBKNH-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM24789 (6-methoxy-2,2-dimethyl-2H,5H,10H-benzo[g]chromene-...) Show SMILES COc1cccc2C(=O)C3=C(C=CC(C)(C)O3)C(=O)c12 |c:11,t:9| Show InChI InChI=1S/C16H14O4/c1-16(2)8-7-10-13(17)12-9(14(18)15(10)20-16)5-4-6-11(12)19-3/h4-8H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.13E+3	n/a	n/a	n/a	n/a	6.5	37
Bryn Mawr College					Assay Description The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...				J Med Chem 51: 1706-18 (2008) Article DOI: 10.1021/jm7014155 BindingDB Entry DOI: 10.7270/Q2VD6WSV
					More data for this Ligand-Target Pair