null
SMILES: OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1sc2ccccc2c1C1CC1
InChI Key: InChIKey=AETNLFSVAXYNAB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential M8 protein (Canis lupus familiaris (Dog)) | BDBM248789 (US9434711, 755) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | 37 |
Janssen Pharmaceutica, N.V. US Patent | Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi... | US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6 | |||||||||||
More data for this Ligand-Target Pair |