BDBM249149 US9453038, 27
SMILES: CN1C(CCC1=O)c1cc2[nH]c(cc2cc1Oc1ccc(CC(O)=O)cc1)-c1ccccn1
InChI Key:
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human)) | BDBM249149 (US9453038, 27) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 23.8 | n/a | n/a | n/a | 30 |
Merck Sharp & Dohme Corp. US Patent | Assay Description To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E.... | US Patent US9453038 (2016) BindingDB Entry DOI: 10.7270/Q23X85KK | |||||||||||
More data for this Ligand-Target Pair |