BDBM249313 US9458145, 1020-289
SMILES: Cc1noc(C)c1-c1cc(c2nc([nH]c2c1)C1CC1)C(O)(C1CCCO1)c1cccnn1
InChI Key:
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 Bromo 2 domain(BRD4 BD2) (Homo sapiens (Human)) | BDBM249313 (US9458145, 1020-289) | GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Gilead Sciences, Inc. US Patent | Assay Description The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi... | US Patent US9458145 (2016) BindingDB Entry DOI: 10.7270/Q26Q1W53 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 Bromo 1 domain(BRD4 BD1) (Homo sapiens (Human)) | BDBM249313 (US9458145, 1020-289) | GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Gilead Sciences, Inc. US Patent | Assay Description The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi... | US Patent US9458145 (2016) BindingDB Entry DOI: 10.7270/Q26Q1W53 | |||||||||||
More data for this Ligand-Target Pair |