BDBM24961 Urea
SMILES: NC(N)=O
InChI Key: InChIKey=XSQUKJJJFZCRTK-UHFFFAOYSA-N
Data: 1 KI
PDB links: 79 PDB IDs match this monomer. 431 PDB IDs contain this monomer as substructures. 431 PDB IDs contain inhibitors having a similarity of 90% to this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...) | BDBM24961 (Urea) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 6.47E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Jishou University Curated by ChEMBL | Assay Description Substrate inhibition of Helicobacter pylori urease in presence of >4 mM urea by indophenol method | Bioorg Med Chem 24: 4519-4527 (2016) Article DOI: 10.1016/j.bmc.2016.07.052 | |||||||||||
More data for this Ligand-Target Pair |