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BDBM249643 US9447038, 71

SMILES: Cc1cc(CN(CC2CCC2)[C@@H](CC(O)=O)c2ccc(Cl)cc2)ccc1OCCN1C(=O)CCC1=O

InChI Key: InChIKey=NANCPBYYSGHPQX-DEOSSOPVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249643   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C motif chemokine 10 (CXCL10)


(Homo sapiens (Human))		BDBM249643
PNG
(US9447038, 71)
Show SMILES Cc1cc(CN(CC2CCC2)[C@@H](CC(O)=O)c2ccc(Cl)cc2)ccc1OCCN1C(=O)CCC1=O |r|
Show InChI InChI=1S/C28H33ClN2O5/c1-19-15-21(5-10-25(19)36-14-13-31-26(32)11-12-27(31)33)18-30(17-20-3-2-4-20)24(16-28(34)35)22-6-8-23(29)9-7-22/h5-10,15,20,24H,2-4,11-14,16-18H2,1H3,(H,34,35)/t24-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 54n/an/an/an/an/a25



Sanofi

US Patent


Assay Description
The composition of the binding assay buffer is determined in a course of detailed optimization procedure. This resulted in a binding assay buffer con...

US Patent US9447038 (2016)


BindingDB Entry DOI: 10.7270/Q29G5KQK
More data for this
Ligand-Target Pair