BDBM249657 US9447038, 85

SMILES: CCCN(Cc1ccc(OCCN2C(=O)CCC2=O)c(CC)c1)C(CC(O)=O)c1ccc(Cl)cc1

InChI Key: InChIKey=QSTHLMTXAYUQJT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C motif chemokine 10 (CXCL10) (Homo sapiens (Human))	BDBM249657 (US9447038, 85) Show SMILES CCCN(Cc1ccc(OCCN2C(=O)CCC2=O)c(CC)c1)C(CC(O)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C27H33ClN2O5/c1-3-13-29(23(17-27(33)34)21-6-8-22(28)9-7-21)18-19-5-10-24(20(4-2)16-19)35-15-14-30-25(31)11-12-26(30)32/h5-10,16,23H,3-4,11-15,17-18H2,1-2H3,(H,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description The composition of the binding assay buffer is determined in a course of detailed optimization procedure. This resulted in a binding assay buffer con...				US Patent US9447038 (2016) BindingDB Entry DOI: 10.7270/Q29G5KQK
					More data for this Ligand-Target Pair