BDBM249696 US9447038, 124

SMILES: COc1cc(CN(CC2CC2)C(CC(O)=O)c2ccc(Cl)c(Cl)c2)ccc1OCCn1c(=O)ccn(C)c1=O

InChI Key: InChIKey=UBFQUEJRKRXITC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249696   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C motif chemokine 10 (CXCL10) (Homo sapiens (Human))	BDBM249696 (US9447038, 124) Show SMILES COc1cc(CN(CC2CC2)C(CC(O)=O)c2ccc(Cl)c(Cl)c2)ccc1OCCn1c(=O)ccn(C)c1=O Show InChI InChI=1S/C28H31Cl2N3O6/c1-31-10-9-26(34)33(28(31)37)11-12-39-24-8-5-19(13-25(24)38-2)17-32(16-18-3-4-18)23(15-27(35)36)20-6-7-21(29)22(30)14-20/h5-10,13-14,18,23H,3-4,11-12,15-17H2,1-2H3,(H,35,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description The composition of the binding assay buffer is determined in a course of detailed optimization procedure. This resulted in a binding assay buffer con...				US Patent US9447038 (2016) BindingDB Entry DOI: 10.7270/Q29G5KQK
					More data for this Ligand-Target Pair