BDBM249718 US9447038, 146

SMILES: COc1cc(CN(CC2CCCC2)C(CC(O)=O)c2ccc3OCCc3c2)ccc1OCCN1C(=O)CCC1=O

InChI Key: InChIKey=VMKKWKQRLVWVKB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249718   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C motif chemokine 10 (CXCL10) (Homo sapiens (Human))	BDBM249718 (US9447038, 146) Show SMILES COc1cc(CN(CC2CCCC2)C(CC(O)=O)c2ccc3OCCc3c2)ccc1OCCN1C(=O)CCC1=O Show InChI InChI=1S/C31H38N2O7/c1-38-28-16-22(6-8-27(28)40-15-13-33-29(34)10-11-30(33)35)20-32(19-21-4-2-3-5-21)25(18-31(36)37)23-7-9-26-24(17-23)12-14-39-26/h6-9,16-17,21,25H,2-5,10-15,18-20H2,1H3,(H,36,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description The composition of the binding assay buffer is determined in a course of detailed optimization procedure. This resulted in a binding assay buffer con...				US Patent US9447038 (2016) BindingDB Entry DOI: 10.7270/Q29G5KQK
					More data for this Ligand-Target Pair