BDBM24985 (5E)-5-{[5-(4-fluorophenyl)furan-2-yl]methylidene}-1-(2-methylphenyl)-1,3-diazinane-2,4,6-trione::5-(furan-2-ylmethylene) pyrimidine-2,4,6-trione derivative, 2

SMILES: Cc1ccccc1N1C(=O)NC(=O)C(=Cc2ccc(o2)-c2ccc(F)cc2)C1=O

InChI Key: InChIKey=SYRBIFBMFWRKTD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty Acid Synthase (Homo sapiens (Human))	BDBM24985 ((5E)-5-{[5-(4-fluorophenyl)furan-2-yl]methylidene}...) Show SMILES Cc1ccccc1N1C(=O)NC(=O)C(=Cc2ccc(o2)-c2ccc(F)cc2)C1=O |w:14.15| Show InChI InChI=1S/C22H15FN2O4/c1-13-4-2-3-5-18(13)25-21(27)17(20(26)24-22(25)28)12-16-10-11-19(29-16)14-6-8-15(23)9-7-14/h2-12H,1H3,(H,24,26,28)	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	910	-8.57	n/a	n/a	n/a	n/a	n/a	7.5	37
Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				Mol Cancer Ther 6: 2120-6 (2007) Article DOI: 10.1158/1535-7163.MCT-07-0187 BindingDB Entry DOI: 10.7270/Q2F769V8
					More data for this Ligand-Target Pair