BDBM25006 4-[4-(3-aminoprop-1-yn-1-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine::oxadiazole-containing compound, 13

SMILES: CCn1c(nc2c(ncc(OCCCN)c12)C#CCN)-c1nonc1N

InChI Key: InChIKey=AOKADEMCVOQECP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM25006 (4-[4-(3-aminoprop-1-yn-1-yl)-7-(3-aminopropoxy)-1-...) Show SMILES CCn1c(nc2c(ncc(OCCCN)c12)C#CCN)-c1nonc1N Show InChI InChI=1S/C16H20N8O2/c1-2-24-14-11(25-8-4-7-18)9-20-10(5-3-6-17)12(14)21-16(24)13-15(19)23-26-22-13/h9H,2,4,6-8,17-18H2,1H3,(H2,19,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	7.5	22
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha 1 (Homo sapiens (Human))	BDBM25006 (4-[4-(3-aminoprop-1-yn-1-yl)-7-(3-aminopropoxy)-1-...) Show SMILES CCn1c(nc2c(ncc(OCCCN)c12)C#CCN)-c1nonc1N Show InChI InChI=1S/C16H20N8O2/c1-2-24-14-11(25-8-4-7-18)9-20-10(5-3-6-17)12(14)21-16(24)13-15(19)23-26-22-13/h9H,2,4,6-8,17-18H2,1H3,(H2,19,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM25006 (4-[4-(3-aminoprop-1-yn-1-yl)-7-(3-aminopropoxy)-1-...) Show SMILES CCn1c(nc2c(ncc(OCCCN)c12)C#CCN)-c1nonc1N Show InChI InChI=1S/C16H20N8O2/c1-2-24-14-11(25-8-4-7-18)9-20-10(5-3-6-17)12(14)21-16(24)13-15(19)23-26-22-13/h9H,2,4,6-8,17-18H2,1H3,(H2,19,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair