BDBM250651 US9447148, 9.20
SMILES: NC(=N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CCC(=O)NCC[C@H](NC1=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)NC(=O)C1CCCCC1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocyte-stimulating hormone receptor (Homo sapiens (Human)) | BDBM250651 (US9447148, 9.20) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0250 | -15.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
Palatin Technologies, Inc. US Patent | Assay Description A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-... | US Patent US9447148 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HD2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM250651 (US9447148, 9.20) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 165 | -9.62 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
Palatin Technologies, Inc. US Patent | Assay Description A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-... | US Patent US9447148 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HD2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocyte-stimulating hormone receptor (Homo sapiens (Human)) | BDBM250651 (US9447148, 9.20) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.00400 | n/a | n/a | 7.5 | 37 |
Palatin Technologies, Inc. US Patent | Assay Description Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ... | US Patent US9447148 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HD2 | |||||||||||
More data for this Ligand-Target Pair |