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BDBM251328 US9452990, 8

SMILES: CC[C@H]1CN(CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1)C(=O)\C=C\c1ccc(cc1)C#N

InChI Key: InChIKey=ALMZPRSACKMWKG-XVHHSVOONA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251328   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251328
PNG
(US9452990, 8)
Show SMILES CC[C@H]1CN(CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1)C(=O)\C=C\c1ccc(cc1)C#N
Show InChI InChI=1/C26H27FN6O3/c1-4-18-15-32(21(34)10-9-16-5-7-17(14-28)8-6-16)11-12-33(18)26-30-23-19(25(29)31-26)13-20(35-2)24(36-3)22(23)27/h5-10,13,18H,4,11-12,15H2,1-3H3,(H2,29,30,31)/b10-9+/t18-/s2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


Citation and Details
More data for this
Ligand-Target Pair