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BDBM251329 US9452990, 9

SMILES: CCC[C@H]1CN(CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1)C(=O)\C=C\c1ccc(cc1)C#N

InChI Key: InChIKey=POOFHGGOBNJKBJ-YOZXTORLNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251329   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251329
PNG
(US9452990, 9)
Show SMILES CCC[C@H]1CN(CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1)C(=O)\C=C\c1ccc(cc1)C#N
Show InChI InChI=1/C27H29FN6O3/c1-4-5-19-16-33(22(35)11-10-17-6-8-18(15-29)9-7-17)12-13-34(19)27-31-24-20(26(30)32-27)14-21(36-2)25(37-3)23(24)28/h6-11,14,19H,4-5,12-13,16H2,1-3H3,(H2,30,31,32)/b11-10+/t19-/s2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


Citation and Details
More data for this
Ligand-Target Pair