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BDBM251342 US9452990, 22

SMILES: COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)c1cc2cc(F)cc(F)c2[nH]1

InChI Key: InChIKey=NEVVESYXCAOSBP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251342   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251342
PNG
(US9452990, 22)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)c1cc2cc(F)cc(F)c2[nH]1
Show InChI InChI=1S/C23H21F3N6O3/c1-34-16-10-13-19(17(26)20(16)35-2)29-23(30-21(13)27)32-5-3-31(4-6-32)22(33)15-8-11-7-12(24)9-14(25)18(11)28-15/h7-10,28H,3-6H2,1-2H3,(H2,27,29,30)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 17n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


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More data for this
Ligand-Target Pair