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BDBM251348 US9452990, 28

SMILES: COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(C[C@@H]1c1ccccc1)C(=O)c1cc2cc(ccc2[nH]1)C#N

InChI Key: InChIKey=CIEFXUNJWFUFJA-QWVACARCNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251348   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251348
PNG
(US9452990, 28)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(C[C@@H]1c1ccccc1)C(=O)c1cc2cc(ccc2[nH]1)C#N
Show InChI InChI=1/C30H26FN7O3/c1-40-24-14-20-26(25(31)27(24)41-2)35-30(36-28(20)33)38-11-10-37(16-23(38)18-6-4-3-5-7-18)29(39)22-13-19-12-17(15-32)8-9-21(19)34-22/h3-9,12-14,23,34H,10-11,16H2,1-2H3,(H2,33,35,36)/t23-/s2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


Citation and Details
More data for this
Ligand-Target Pair