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BDBM251357 US9452990, 37

SMILES: COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](N)c1ccsc1

InChI Key: InChIKey=WSSALBIKOMMCAP-CQSZACIVSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251357   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cobra venom factor/Complement factor B/Complement factor D


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)		BDBM251357
PNG
(US9452990, 37)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](N)c1ccsc1 |r|
Show InChI InChI=1S/C21H25FN6O3S/c1-30-15-9-13-18(17(22)19(15)31-2)25-21(26-20(13)24)28-6-4-27(5-7-28)16(29)10-14(23)12-3-8-32-11-12/h3,8-9,11,14H,4-7,10,23H2,1-2H3,(H2,24,25,26)/t14-/m1/s1
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
US Patent
n/an/a 40n/an/an/an/a7.425



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...

US Patent US9452990 (2016)


BindingDB Entry DOI: 10.7270/Q2H130Z9
More data for this
Ligand-Target Pair