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BDBM251363 US9452990, 43

SMILES: COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](N)c1cccc(c1)C#N

InChI Key: InChIKey=BDFQCRLDXMIKFS-AGDOHHJYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251363   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251363
PNG
(US9452990, 43)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](N)c1cccc(c1)C#N
Show InChI InChI=1/C24H26FN7O3/c1-34-18-11-16-21(20(25)22(18)35-2)29-24(30-23(16)28)32-8-6-31(7-9-32)19(33)12-17(27)15-5-3-4-14(10-15)13-26/h3-5,10-11,17H,6-9,12,27H2,1-2H3,(H2,28,29,30)/t17-/s2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 40n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


Citation and Details
More data for this
Ligand-Target Pair