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BDBM251384 US9452990, 64

SMILES: CC[C@H]1CN(CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1)C(=O)C[C@@H](N)c1ccc(cc1)C#N

InChI Key: InChIKey=QDDVVUTUTGYZNH-ZSFWTHPBNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251384   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251384
PNG
(US9452990, 64)
Show SMILES CC[C@H]1CN(CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1)C(=O)C[C@@H](N)c1ccc(cc1)C#N
Show InChI InChI=1/C26H30FN7O3/c1-4-17-14-33(21(35)12-19(29)16-7-5-15(13-28)6-8-16)9-10-34(17)26-31-23-18(25(30)32-26)11-20(36-2)24(37-3)22(23)27/h5-8,11,17,19H,4,9-10,12,14,29H2,1-3H3,(H2,30,31,32)/t17-,19+/s2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


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More data for this
Ligand-Target Pair