BindingDB logo
myBDB logout

BDBM251405 US9452990, 87

SMILES: COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](NC(CF)CF)c1ccc(F)cc1

InChI Key: InChIKey=BIXBURHTSQGAPR-TWYLJJHKNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251405   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251405
PNG
(US9452990, 87)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](NC(CF)CF)c1ccc(F)cc1
Show InChI InChI=1/C26H30F4N6O3/c1-38-20-11-18-23(22(30)24(20)39-2)33-26(34-25(18)31)36-9-7-35(8-10-36)21(37)12-19(32-17(13-27)14-28)15-3-5-16(29)6-4-15/h3-6,11,17,19,32H,7-10,12-14H2,1-2H3,(H2,31,33,34)/t19-/s2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 40n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


Citation and Details
More data for this
Ligand-Target Pair