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SMILES: COc1cc2c(N)nc(nc2c(F)c1OC)N1[C@@H](C)CN(C[C@H]1C)C(=O)C[C@@H](NC(C)C)c1ccc(cc1)C#N

InChI Key: InChIKey=FLRSUHACPSGKAZ-KGVIQGDOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251415   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cobra venom factor/Complement factor B/Complement factor D


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)		BDBM251415
PNG
(US9452990, 97)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1[C@@H](C)CN(C[C@H]1C)C(=O)C[C@@H](NC(C)C)c1ccc(cc1)C#N |r|
Show InChI InChI=1S/C29H36FN7O3/c1-16(2)33-22(20-9-7-19(13-31)8-10-20)12-24(38)36-14-17(3)37(18(4)15-36)29-34-26-21(28(32)35-29)11-23(39-5)27(40-6)25(26)30/h7-11,16-18,22,33H,12,14-15H2,1-6H3,(H2,32,34,35)/t17-,18+,22-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/a7.425



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...

US Patent US9452990 (2016)


BindingDB Entry DOI: 10.7270/Q2H130Z9
More data for this
Ligand-Target Pair