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BDBM251417 US9452990, 99

SMILES: COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](N1CCCCC1)c1ccc(F)cc1

InChI Key: InChIKey=JKFYJXQDIKEEKI-RNZRUAGMNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251417   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251417
PNG
(US9452990, 99)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](N1CCCCC1)c1ccc(F)cc1
Show InChI InChI=1/C28H34F2N6O3/c1-38-22-16-20-25(24(30)26(22)39-2)32-28(33-27(20)31)36-14-12-35(13-15-36)23(37)17-21(34-10-4-3-5-11-34)18-6-8-19(29)9-7-18/h6-9,16,21H,3-5,10-15,17H2,1-2H3,(H2,31,32,33)/t21-/s2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


Citation and Details
More data for this
Ligand-Target Pair