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SMILES: COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](NC(C)C)c1ccc(F)cn1

InChI Key: InChIKey=DYRIZPIFTPTBFX-GOSISDBHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251419   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cobra venom factor/Complement factor B/Complement factor D


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)		BDBM251419
PNG
(US9452990, 101)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](NC(C)C)c1ccc(F)cn1 |r|
Show InChI InChI=1S/C25H31F2N7O3/c1-14(2)30-18(17-6-5-15(26)13-29-17)12-20(35)33-7-9-34(10-8-33)25-31-22-16(24(28)32-25)11-19(36-3)23(37-4)21(22)27/h5-6,11,13-14,18,30H,7-10,12H2,1-4H3,(H2,28,31,32)/t18-/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/a7.425



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...

US Patent US9452990 (2016)


BindingDB Entry DOI: 10.7270/Q2H130Z9
More data for this
Ligand-Target Pair