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BDBM251439 US9452990, 121

SMILES: COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(C[C@@H]1c1ccccc1)C(=O)C[C@@H]1CCCCN1

InChI Key: InChIKey=FSUFTIXGMHRKIG-HOFUVJEBNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251439   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251439
PNG
(US9452990, 121)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(C[C@@H]1c1ccccc1)C(=O)C[C@@H]1CCCCN1
Show InChI InChI=1/C27H33FN6O3/c1-36-21-15-19-24(23(28)25(21)37-2)31-27(32-26(19)29)34-13-12-33(16-20(34)17-8-4-3-5-9-17)22(35)14-18-10-6-7-11-30-18/h3-5,8-9,15,18,20,30H,6-7,10-14,16H2,1-2H3,(H2,29,31,32)/t18-,20+/s2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


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More data for this
Ligand-Target Pair