BDBM251681 US10100018, Example 17::US9464060, 17

SMILES: OC(=O)c1ccc(CN(CCCc2cccc(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1

InChI Key: InChIKey=UQNKBZRQZWHMCX-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 251681   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysophosphatidic acid receptor 5 (LPA5) (Homo sapiens (Human))	BDBM251681 (US10100018, Example 17 | US9464060, 17) Show SMILES OC(=O)c1ccc(CN(CCCc2cccc(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 Show InChI InChI=1S/C30H25F2NO4/c31-25-7-3-5-21(19-25)6-4-18-33(20-22-10-12-24(13-11-22)30(35)36)29(34)23-14-16-26(17-15-23)37-28-9-2-1-8-27(28)32/h1-3,5,7-17,19H,4,6,18,20H2,(H,35,36)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA5 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...				US Patent US9464060 (2016) BindingDB Entry DOI: 10.7270/Q23R0RT0
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM251681 (US10100018, Example 17 | US9464060, 17) Show SMILES OC(=O)c1ccc(CN(CCCc2cccc(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 Show InChI InChI=1S/C30H25F2NO4/c31-25-7-3-5-21(19-25)6-4-18-33(20-22-10-12-24(13-11-22)30(35)36)29(34)23-14-16-26(17-15-23)37-28-9-2-1-8-27(28)32/h1-3,5,7-17,19H,4,6,18,20H2,(H,35,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...				US Patent US10100018 (2018) BindingDB Entry DOI: 10.7270/Q2PR7Z0N
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM251681 (US10100018, Example 17 | US9464060, 17) Show SMILES OC(=O)c1ccc(CN(CCCc2cccc(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 Show InChI InChI=1S/C30H25F2NO4/c31-25-7-3-5-21(19-25)6-4-18-33(20-22-10-12-24(13-11-22)30(35)36)29(34)23-14-16-26(17-15-23)37-28-9-2-1-8-27(28)32/h1-3,5,7-17,19H,4,6,18,20H2,(H,35,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...				US Patent US10100018 (2018) BindingDB Entry DOI: 10.7270/Q2PR7Z0N
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM251681 (US10100018, Example 17 | US9464060, 17) Show SMILES OC(=O)c1ccc(CN(CCCc2cccc(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 Show InChI InChI=1S/C30H25F2NO4/c31-25-7-3-5-21(19-25)6-4-18-33(20-22-10-12-24(13-11-22)30(35)36)29(34)23-14-16-26(17-15-23)37-28-9-2-1-8-27(28)32/h1-3,5,7-17,19H,4,6,18,20H2,(H,35,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	37
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...				US Patent US9464060 (2016) BindingDB Entry DOI: 10.7270/Q23R0RT0
					More data for this Ligand-Target Pair